LPAR1, lysophosphatidic acid receptor 1, 1902

N. diseases: 145; N. variants: 11
Disease: Triple-Negative Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4722518
Disease: Triple-Negative Breast Carcinoma
Triple-Negative Breast Carcinoma 		0.020 AlteredExpression disease BEFREE We took advantage of elevated expression of lysophosphatidic acid receptor 1 (LPAR<sub>1</sub>) in triple negative breast cancer (TNBC) tissues to target decitabine (DAC) and panobinostat (PAN) to breast cancer cells. 30883132 2019
CUI: C4722518
Disease: Triple-Negative Breast Carcinoma
Triple-Negative Breast Carcinoma 		0.020 Biomarker disease BEFREE The data argue against LPAR1 and fibrosis as monotherapy targets for metastasis prevention in triple-negative breast cancer and ovarian cancer. 29805748 2018