EDN1, endothelin 1, 1906

N. diseases: 679; N. variants: 23
Disease: Cardiomegaly ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.510 Biomarker phenotype CTD_human PPARα activation inhibits endothelin-1-induced cardiomyocyte hypertrophy by prevention of NFATc4 binding to GATA-4. 22198280 2012
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.510 GeneticVariation phenotype LHGDN Screening of the endothelin1 gene (EDN1) in a cohort of patients with essential left ventricular hypertrophy. 17335511 2007
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.510 ModifyingMutation phenotype RGD Endothelin-1 and its binding sites are upregulated in pressure overload cardiac hypertrophy. 7771559 1995