EDN1, endothelin 1, 1906

N. diseases: 679; N. variants: 23
Disease: Agnosia for Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		0.010 AlteredExpression disease BEFREE The present study assessed the effects of ETBR activation and the role of endogenous opioid analgesia in carcinoma pain using an orthotopic cancer pain mouse model. mRNA expression analysis showed that ET-1 was nearly doubled while ETBR was significantly down-regulated in a human oral SCC cell line compared to normal oral keratinocytes (NOK). 20206445 2010