EDN1, endothelin 1, 1906

N. diseases: 679; N. variants: 23
Disease: Renal Insufficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.320 Biomarker disease BEFREE A number of vasoactive mediators including proprotein convertase subtilisin-kexin type 9 (PCSK9), endothelin-1, nitric oxide, and angiotensin II have fundamental roles in the pathophysiology of atherosclerotic events; moreover, their levels are affected by dyslipidemia and oxidative stress due to renal dysfunction. 31641998 2019
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.320 GeneticVariation disease BEFREE Role of the endothelin-1 gene locus for renal impairment in the general nondiabetic population. 14514737 2003
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.320 Biomarker disease CTD_human Effects of endothelin-1 on renal function in humans: implications for physiology and pathophysiology. 7967349 1994