EDN3, endothelin 3, 1908

N. diseases: 107; N. variants: 16
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 AlteredExpression disease LHGDN Endothelin-3 is produced by metastatic melanoma cells and promotes melanoma cell survival. 18346402 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.030 AlteredExpression disease LHGDN Endothelin signaling axis activates osteopontin expression through PI3 kinase pathway in A375 melanoma cells. 18722093 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE Expression of endothelin-B receptor gradually increases as melanocytic lesions progress to melanoma, suggesting that endothelin-B receptor and its ligands, endothelin-1 and endothelin- 3, play a role in the melanoma progression. 15838263 2004