EDNRA, endothelin receptor type A, 1909

N. diseases: 427; N. variants: 29
Disease: Low Tension Glaucoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0152136
Disease: Low Tension Glaucoma
Low Tension Glaucoma 		0.030 GeneticVariation disease BEFREE The purpose of this study was to determine whether four single nucleotide polymorphisms (SNPs) of <i>endothelin and endothelin receptor type A genes</i> can constitute a risk factor for normal tension glaucoma (NTG) and high tension glaucoma (HTG). 27777505 2016
CUI: C0152136
Disease: Low Tension Glaucoma
Low Tension Glaucoma 		0.030 GeneticVariation disease BEFREE The polymorphism of EDNRA:c.*1222C > T was significantly associated with NTG (p = 0.028, OR = 3.33, 95% CI 1.05-10.24). 16971893 2006
CUI: C0152136
Disease: Low Tension Glaucoma
Low Tension Glaucoma 		0.030 GeneticVariation disease BEFREE The GG genotype of EDNRA/C+70G was associated with worse visual field defects in NTG patients (p=0.014; Mann-Whitney U test, and p=0.027; logistic regression analysis). 15988412 2005