EDNRA, endothelin receptor type A, 1909

N. diseases: 427; N. variants: 29
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease BEFREE Targeting endothelin-1 receptor/β-arrestin1 network for the treatment of ovarian cancer. 28758529 2017
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease CTD_human To maximize the safety and efficacy of ETAR-targeted OC therapy, we investigated the role of other G protein subunits such as Gαs in the ETAR-mediated ovarian oncogenic signaling. 25194819 2014
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease BEFREE To maximize the safety and efficacy of ETAR-targeted OC therapy, we investigated the role of other G protein subunits such as Gαs in the ETAR-mediated ovarian oncogenic signaling. 25194819 2014
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease BEFREE The effects of luteinizing hormone (LH), a gonadotropic hormone implicated in the development of ovarian cancer, are mediated by specific binding to its G protein-coupled receptor, the LH receptor (LHR). 19010824 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease LHGDN Integrin-linked kinase functions as a downstream mediator of endothelin-1 to promote invasive behavior in ovarian carcinoma. 16648553 2006
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease BEFREE Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. 10537322 1999