EFNA5, ephrin A5, 1946

N. diseases: 66; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury
0.300 Biomarker disease CTD_human Effect of furosemide infusion on renal hemodynamics and angiogenesis gene expression in acute renal ischemia/reperfusion. 16526316 2006
CUI: C0002902
Disease: Anencephaly
Anencephaly
0.200 Biomarker disease MGD Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping. 10774725 2000
CUI: C0002902
Disease: Anencephaly
Anencephaly
0.200 Biomarker disease MGD Regulation of repulsion versus adhesion by different splice forms of an Eph receptor. 11089974 2000
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.120 GeneticVariation disease GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203 2019
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.120 Biomarker disease BEFREE A recent report has suggested that copy number variations in four genes (GRIK3, EFNA5, AKAP5 and CACNG2) may be associated with schizophrenia. 17826036 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.120 GeneticVariation disease BEFREE Moldin et al.(1) have identified a cluster of Minnesota Multiphasic Personality Inventory (MMPI) scales that discriminate adolescents at risk for schizophrenia from those not at risk. 10408265 1999
CUI: C0021704
Disease: Intelligence
Intelligence
0.100 GeneticVariation phenotype GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203 2019
CUI: C0037369
Disease: Smoking
Smoking
0.100 GeneticVariation phenotype GWASCAT Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. 30643258 2019
CUI: C1305855
Disease: Body mass index
Body mass index
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0596887
Disease: mathematical ability
mathematical ability
0.100 GeneticVariation phenotype GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
CUI: C4049938
Disease: Physical Activity Measurement
Physical Activity Measurement
0.100 GeneticVariation phenotype GWASCAT GWAS identifies 14 loci for device-measured physical activity and sleep duration. 30531941 2018
CUI: C4315130
Disease: Hippocampal atrophy
Hippocampal atrophy
0.100 GeneticVariation phenotype GWASCAT Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. 19668339 2009
CUI: C4315130
Disease: Hippocampal atrophy
Hippocampal atrophy
0.100 GeneticVariation phenotype GWASDB Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. 19668339 2009
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.030 Biomarker disease BEFREE The role of tissue-resident memory T (T<sub>RM</sub>) cells in breast cancer progression has been difficult to study.Savas et al.[1] (Nat.Med. 30077643 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 GeneticVariation group BEFREE Stroke Risk and Treatment in Patients with Atrial Fibrillation and Low CHA<sub>2</sub>DS<sub>2</sub>-VASc Scores: Findings From the ORBIT-AF I and II Registries. 30369317 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.030 Biomarker disease BEFREE The role of tissue-resident memory T (T<sub>RM</sub>) cells in breast cancer progression has been difficult to study.Savas et al.[1] (Nat.Med. 30077643 2018
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.030 GeneticVariation disease BEFREE There are major flaws with the analyses in the Vistisen et al (1) cohort study examining if night shift work is a short-term risk factor for breast cancer. 27935621 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 GeneticVariation group BEFREE Patients from GARFIELD-AF were less likely to be white (63% vs 89% for ORBIT-AF I and 86% for ORBIT-AF II) or have coronary artery disease (19% vs 36% and 27%), but had similar stroke risk (85% CHA<sub>2</sub>DS<sub>2</sub>-VASc ≥2 vs 91% and 85%) and lower bleeding risk (11% with HAS-BLED ≥3 vs 24% and 15%). 29223431 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.030 GeneticVariation disease BEFREE There are major flaws with the analyses in the Vistisen et al (1) cohort study examining if night shift work is a short-term risk factor for breast cancer. 27935621 2017
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.030 Biomarker disease BEFREE We profiled a set of 50 fresh frozen (FF) breast cancer samples and assigned class labels according to the signature and method by van 't Veer et al 1 and then profiled 50 matched FFPET samples to test how well the FFPET data predicted the class labels. 19638234 2009
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.030 Biomarker disease BEFREE We profiled a set of 50 fresh frozen (FF) breast cancer samples and assigned class labels according to the signature and method by van 't Veer et al 1 and then profiled 50 matched FFPET samples to test how well the FFPET data predicted the class labels. 19638234 2009
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 Biomarker group BEFREE For growth-inhibitory molecules, myelin-associated glycoprotein and ephrin A5 are uniquely induced in the aged brain; chondroitin sulfate proteoglycans and oligodendrocyte myelin glycoprotein are induced at earlier time points; and Nogo-A, semaphorin IIIa and NG2 decline in aged vs. young adult after stroke. 16782355 2006
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.020 Biomarker disease BEFREE The beneficial effects of ALA or AL-1 on the most important parameters of UC were reviewed; also, studies were considered separately in mice and rats. 30362597 2019
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.020 Biomarker disease BEFREE In the present study, we aimed to investigate the therapeutic potential of AL-1 against DSS-induced UC in mice and to define its mechanisms of action. 31687082 2019
CUI: C0029182
Disease: orbit (eye disorders)
orbit (eye disorders)
0.020 Biomarker group BEFREE Stroke Risk and Treatment in Patients with Atrial Fibrillation and Low CHA<sub>2</sub>DS<sub>2</sub>-VASc Scores: Findings From the ORBIT-AF I and II Registries. 30369317 2018