Osteosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
TP53, IGF1, JUN, BGLAP, ATM, MAPK1, ATF3, H2AFX, BAX, CDKN2A, and EGF were identified as the potential targets of biochanin A against osteosarcoma.
|
30723510 |
2019 |
Osteosarcoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Commonly described mutations include mutations in epidermal growth factor (<i>EGFR</i>) & <i>BRAF</i> and translocations in anaplastic lymphoma kinase (<i>ALK</i>) & rat osteosarcoma (<i>ROS1</i>).
|
30622805 |
2018 |
Osteosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
However, whether Ezrin mediates NF-κB in EGF-induced osteosarcoma is unknown.
|
29628496 |
2018 |
Osteosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The objective of this study was to explore the effect and mechanism of downregulating epidermal growth factor-like domain 7 expression in a human osteosarcoma cell line on the biological function of co-cultured human umbilical vein endothelial cells.
|
29363485 |
2018 |
Osteosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The association of the expression of HER receptors in osteosarcoma with clinicopathological parameters was analyzed using χ<sup>2</sup> test and Fishers exact test.
|
30008917 |
2018 |
Osteosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Cyclic Guanosine Monophosphate (cGMP)-Dependent Protein Kinase II Blocks Epidermal Growth Factor (EGF)/Epidermal Growth Factor Receptor (EGFR)-Induced Biological Effects on Osteosarcoma Cells.
|
29617357 |
2018 |
Osteosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rho A Regulates Epidermal Growth Factor-Induced Human Osteosarcoma MG63 Cell Migration.
|
29751634 |
2018 |
Osteosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Macropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells.
|
29018288 |
2017 |
Osteosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The role of epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1) in osteosarcoma remains unknown.
|
25987128 |
2015 |
Osteosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Western blotting and a quantitative real-time RT-PCR assay developed for T-cadherin showed that estradiol, progesterone, EGF, dexamethasone and factors in serum were involved in transcriptional and post-transcriptional regulation of T-cadherin in human osteosarcoma cells; the effects observed were opposite to those described for T-cadherin's ligand, adiponectin.
|
16516410 |
2006 |
Osteosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Previous reports suggest that the human epidermal growth factor 2 (HER-2/neu) receptor may be overexpressed in osteosarcoma.
|
16683887 |
2006 |
Osteosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Human epidermal growth factor (Her-2/neu) expression in 25 initial pretreatment osteosarcoma biopsies and 12 posttreatment pulmonary metastatic osteosarcoma resection specimens was assessed by standard immunohistochemical techniques on formalin-fixed paraffin-embedded tissue.
|
12544770 |
2003 |
Osteosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In contrast, expression of TSP-1 was markedly enhanced by TGFbeta1, but not by EGF, in osteosarcoma MG63 cells.
|
11955611 |
2002 |