EGR1, early growth response 1, 1958

N. diseases: 378; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008370
Disease: Cholestasis
Cholestasis
0.320 Biomarker disease BEFREE Early growth response factor 1 (Egr-1) may play a central role in the inflammation induced by cholestasis, and it is also a potential therapeutic target to inhibit the inflammation induced by cholestasis. 30814402 2019
CUI: C0008370
Disease: Cholestasis
Cholestasis
0.320 AlteredExpression disease BEFREE Fibrinogen deficiency increases liver injury and early growth response-1 (Egr-1) expression in a model of chronic xenobiotic-induced cholestasis. 21356363 2011
CUI: C0008370
Disease: Cholestasis
Cholestasis
0.320 Biomarker disease CTD_human Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis. 21224055 2011