AHR, aryl hydrocarbon receptor, 196

N. diseases: 532; N. variants: 20
Disease: Influenza A ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 Biomarker disease BEFREE Early life exposure to chemicals that bind the AHR impairs CD4<sup>+</sup> T cell responses to influenza A virus (IAV) infection in adulthood. 31391494 2019
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 Biomarker disease BEFREE Developmental exposure to AHR binding chemicals causes persistent changes in CD4+ and CD8+ T cell responses later in life, including dampened clonal expansion and differentiation during influenza A virus (IAV) infection. 30412605 2018
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 Biomarker disease BEFREE We report here the comparison of four agents representing different sources of AHR ligands in mice infected with influenza A virus (IAV): TCDD, prototype exogenous AHR agonist; PCB126, pollutant with documented human exposure; ITE, novel pharmaceutical; and FICZ, degradation product of tryptophan. 29379138 2018