AHR, aryl hydrocarbon receptor, 196

N. diseases: 532; N. variants: 20
Disease: estrogen receptor-negative breast cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4733092
Disease: estrogen receptor-negative breast cancer
estrogen receptor-negative breast cancer 		0.030 Biomarker disease BEFREE This nongenomic pathway emanated from the phthalate-induced AhR promoted tumorigenesis of ER-negative breast cancer. 22049059 2012
CUI: C4733092
Disease: estrogen receptor-negative breast cancer
estrogen receptor-negative breast cancer 		0.030 Biomarker disease BEFREE MCDF (40 mg/kg/d) also inhibited lung metastasis of MDA-MB-231 cells in a tail vein injection model, showing that the AHR is a potential new target for treating patients with ER-negative breast cancer, a disease where treatment options and their effectiveness are limited. 22034498 2012
CUI: C4733092
Disease: estrogen receptor-negative breast cancer
estrogen receptor-negative breast cancer 		0.030 Biomarker disease BEFREE These results suggest that the AhR is a potential drug target for treatment of ER-negative breast cancer. 19447902 2009