AHSG, alpha 2-HS glycoprotein, 197

N. diseases: 204; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 AlteredExpression disease BEFREE Affecting the fetuin-A and SIRT1 levels introduces a new known mechanism of probiotic action in diabetes management. 30675190 2019
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 AlteredExpression disease BEFREE <b>Conclusion:</b> Lower fetuin-A levels are associated with an increased risk of all-cause mortality independent of diabetes and inflammation in dialysis patients, and there may be a dose-response relationship between them. 31417425 2019
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker disease BEFREE As a multifunctional protein, fetuin-A has positive effects on health such as calcification, cardiovascular diseases and tumor development processes with various mechanisms, whereas it plays a negative role in the processes of obesity, diabetes and fatty liver disease. 31232084 2019
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker disease BEFREE In conclusion, although there is mechanistic evidence for an effect of fetuin-A on insulin sensitivity and secretion, this study does not support a strong, relevant relationship between circulating fetuin-A and diabetes risk in the general population. 29523632 2018
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 AlteredExpression disease BEFREE Fetuin-A levels increased in association with diabetes in SAT but not in circulation in the obese subjects. 30579336 2018
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 AlteredExpression disease BEFREE Serum fetuin A levels in T1D patients (mean 0.267 ± 0.043 g/L) did not correlate with age, diabetes duration, gender, body mass index (BMI), glycated hemoglobin, serum lipid levels, blood pressure, celiac or thyroid disease, nephropathy, or retinopathy. 29207397 2018
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker disease BEFREE Fetuin-A is a liver-derived circulating protein that is associated with insulin resistance and diabetes. 28643299 2018
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 AlteredExpression disease BEFREE Participants with diabetes and PAD had lower fetuin-A levels than non-PAD diabetic patients. 27899247 2017
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 AlteredExpression disease BEFREE However, it remains unclear whether the association between high levels of fetuin-A and diabetes can be attributed to nonalcoholic fatty liver disease. 27856445 2017
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 GeneticVariation disease BEFREE Plasma fetuin-A is associated with type 2 diabetes, and AHSG, the gene encoding fetuin-A, has been identified as a susceptibility locus for diabetes and metabolic syndrome. 28379451 2017
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 AlteredExpression disease BEFREE Therefore, we examined the effects of 6-month AEX+WL on plasma fetuin-A levels (36-48 hours after the last bout of exercise), aerobic capacity (VO<sub>2max</sub>), body composition, glucose tolerance, and insulin sensitivity (M) in 16 sedentary, overweight-obese older men (age = 60 ± 2 years, BMI = 31 ± 1 kg/m<sup>2</sup>) with no history of cardiovascular disease or diabetes. 28770230 2017
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 AlteredExpression disease BEFREE Other risk factors, including inflammation and diabetes, might lead to lower fetuin-A levels, and/or modify the effect of low fetuin-A on mortality in end-stage renal disease patients. 20605840 2011
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker disease BEFREE In a logistic regression model (N= 101), fetuin-A was significantly (P < 0.05) associated with the presence of carotid plaques independently of age, CVD, diabetes, S-albumin, gender, and inflammation. 15882283 2005