AHSG, alpha 2-HS glycoprotein, 197

N. diseases: 204; N. variants: 18
Disease: Vascular calcification ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE The importance of fetuin-A in vascular calcification in children with chronic kidney disease. 30070080 2019
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE Fetuin-A, which plays a protective role against the atherosclerosis and progression of vascular calcification, is decreased in patients on hemodialysis (HD). 30128921 2018
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE Fetuin-A is a negative acute phase reactant which inhibits calcium-phosphorus precipitation and vascular calcification. 29288724 2018
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE The aim of our study was to determine VC in HD patients, the relationship between VC and 25-OH-vitamin D, fetuin-A, and OPN levels, and independent predictors of VC. 29134617 2018
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE During outpatient visits, plasma samples of all patients were obtained and analyzed for sST2 (hemodynamics and inflammation), galectin-3 (fibrosis and remodeling), GDF-15 (remodeling and inflammation), suPAR (inflammation), and fetuin-A (vascular calcification) by use of ELISA after informed consent. 29652038 2018
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 AlteredExpression phenotype BEFREE We examined the relationships in stable PD patients between phase angle (PhA) and the spectrum of uremic vasculopathy including vascular calcification and arterial stiffness and between PhA and changes in serum fetuin-A levels. 28096437 2018
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE The main purpose of this study was evaluating the correlation between fetuin-A and PTX3 with some biochemical parameters effective upon vascular calcification in HD patients. 29664315 2017
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE Fetuin-A is a member of protease inhibitors that act as an inhibitor of vascular calcification. 24990392 2015
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE We studied the determinants of fetuin-A, a potent circulating calcification inhibitor encoded by the AHSG gene, and tested its association with vascular calcifications and long-term survival and cardiovascular events (CVEs) in RTRs. 21527649 2011
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 GeneticVariation phenotype BEFREE The fetuin-A polymorphism (Thr256Ser) is associated with reduced fetuin levels and accelerated vascular calcification in dialysis patients. 19110009 2009
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE Among these mediators, studies on fetuin-A deserve further attention as clinical studies consistently show that fetuin-A deficiency is associated with vascular calcification, all-cause and cardiovascular mortality in CKD patients. 19004191 2008
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE Vascular calcification and fetuin-A deficiency in chronic kidney disease. 17482094 2007
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE Fetuin-A, also known as alpha(2)-Heremans-Schmid glycoprotein (AHSG), is a circulating plasma protein with inhibitory effects on VC that has been associated with inflammation and CV mortality in HD patients. 17851232 2007
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.100 Biomarker phenotype BEFREE Fetuin-A, a circulating calcium-regulatory glycoprotein that inhibits vascular calcification, is associated with inflammation and outcome in dialysis patients. 15882283 2005