CELA1, chymotrypsin like elastase 1, 1990

N. diseases: 31; N. variants: 0
Disease: Autoimmune Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.020 Biomarker group BEFREE Expression of LT α and β on acinar cells in murine pancreata Tg(Ela1-Lta,b) mice led to chronic pancreatitis and sufficed to reproduce key features of human AIP including the development of autoimmunity and AIP associated secondary extra pancreatic pathologies. 24508087 2014
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.020 AlteredExpression group BEFREE Acinar-specific overexpression of LTαβ (Ela1-LTαβ) in mice led to an autoimmune disorder with various features of AIP. 22863765 2012