|
Learning Disorders
|
0.200 |
Biomarker
|
group |
RGD |
PKC activation during training restores mushroom spine synapses and memory in the aged rat.
|
23545166 |
2013 |
|
Learning Disabilities
|
0.200 |
Biomarker
|
disease |
RGD |
PKC activation during training restores mushroom spine synapses and memory in the aged rat.
|
23545166 |
2013 |
|
Status Epilepticus
|
0.200 |
Biomarker
|
disease |
RGD |
Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity.
|
17577668 |
2007 |
|
Hypothyroidism
|
0.200 |
Biomarker
|
disease |
RGD |
Neuronal HuD gene encoding a mRNA stability regulator is transcriptionally repressed by thyroid hormone.
|
12859688 |
2003 |
|
Sciatic Neuropathy
|
0.200 |
Biomarker
|
disease |
RGD |
Increased expression and localization of the RNA-binding protein HuD and GAP-43 mRNA to cytoplasmic granules in DRG neurons during nerve regeneration.
|
12957493 |
2003 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
|
Smoking
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
|
30643258 |
2019 |
|
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
|
30718901 |
2019 |
|
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.
|
30108127 |
2018 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
|
28991256 |
2017 |
|
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
26426971 |
2015 |
|
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic studies of body mass index yield new insights for obesity biology.
|
25673413 |
2015 |
|
Small cell carcinoma of lung
|
0.060 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to investigate the serum HuD concentration in SCLC patients and the possibility of its utilization as a biomarker of small cell lung cancer.
|
28739747 |
2017 |
|
Small cell carcinoma of lung
|
0.060 |
Biomarker
|
disease |
BEFREE |
Specifically, the N-terminal region of ELAVL4, previously implicated in SCLC-associated autoimmunity, undergoes isoaspartylation in vitro, is recognized by sera from anti-ELAVL4 positive SCLC patients and is highly immunogenic in subcutaneously injected mice and in vitro stimulated human lymphocytes.
|
27725125 |
2016 |
|
Small cell carcinoma of lung
|
0.060 |
AlteredExpression
|
disease |
LHGDN |
Molecular detection of neuron-specific ELAV-like-positive cells in the peripheral blood of patients with small-cell lung cancer.
|
18607064 |
2008 |
|
Small cell carcinoma of lung
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Anti-Hu syndrome is a paraneoplastic neurologic disease seemingly associated with an efficient antitumoral immune response against HuD protein expressed by both small cell lung cancer (SCLC) and neurons.
|
14512168 |
2003 |
|
Small cell carcinoma of lung
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
These results revealed that no aberrant alternative splicing occurred in SCLC not associated with PEM/PSN and the expression of HuD gene was not specific for a particular histologic subtype of human lung cancer.
|
9288629 |
1997 |
|
Small cell carcinoma of lung
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
These results show that the HuD gene is not mutated in lung cancer, including tumors from patients producing anti-HuD antibodies, but HuD expression is an independent marker or determinant of the neuroendocrine differentiation seen in SCLC.
|
8069866 |
1994 |
|
Parkinson Disease
|
0.040 |
Biomarker
|
disease |
BEFREE |
Previous studies indicate that as many as six genes within the PARK10 region (RNF11, UQCRH, HIVEP3, EIF2B3, USP24, ELAVL4) might modify susceptibility or age at onset in Parkinson's disease (PD).
|
24156912 |
2014 |
|
Parkinson Disease
|
0.040 |
Biomarker
|
disease |
LHGDN |
This replication of association with rs967582 in a third cohort further implicates ELAVL4 as a PD susceptibility gene.
|
18587682 |
2008 |
|
Parkinson Disease
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
This replication of association with rs967582 in a third cohort further implicates ELAVL4 as a PD susceptibility gene.
|
18587682 |
2008 |
|
Parkinson Disease
|
0.040 |
Biomarker
|
disease |
BEFREE |
Our data suggest that the association between ELAVL4 and PD previously observed might be explained by a Celtic-founder effect.
|
17230446 |
2007 |
|
Parkinson Disease
|
0.040 |
Biomarker
|
disease |
LHGDN |
SNP 2 (located in the first intron of ELAVL4) showed a strong significant association with AAO of PD (P = 0.006), and SNP 5 (a coding SNP in ELAVL4) showed a moderately significant association (P = 0.035).
|
15827745 |
2005 |
|
Parkinson Disease
|
0.040 |
Biomarker
|
disease |
BEFREE |
SNP 2 (located in the first intron of ELAVL4) showed a strong significant association with AAO of PD (P = 0.006), and SNP 5 (a coding SNP in ELAVL4) showed a moderately significant association (P = 0.035).
|
15827745 |
2005 |
|
Malignant neoplasm of lung
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Molecular analysis of the HuD gene in neuroendocrine lung cancers.
|
19410329 |
2010 |