A2M, alpha-2-macroglobulin, 2

N. diseases: 147; N. variants: 3
Disease: Adult Liposarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278608
Disease: Adult Liposarcoma
Adult Liposarcoma 		0.010 AlteredExpression disease BEFREE Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands such as fatty acids and rosiglitazone increased functional cell surface LRP by 1.5-2.0-fold in primary human adipocytes and in the SW872 human liposarcoma cell line as assessed by activated alpha(2)-macroglobulin binding and degradation. 12551936 2003