ELN, elastin, 2006

N. diseases: 545; N. variants: 61
Disease: Fetal Growth Retardation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.150 Biomarker phenotype BEFREE In summary, the PND 21 rat mediators of vascular remodeling from IUGR and maternal HFD normalize by PND 60 while changes in elastin and arterial stiffness persist. 31225985 2019
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.150 Biomarker phenotype BEFREE However, the larger compliance of elastin in adult IUGR females may contribute to the maintenance of a normal blood pressure level. 29277911 2018
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.150 Biomarker phenotype BEFREE Constitutive modeling demonstrated that a simplified Fung-type hyperelastic model was able to describe the mechanical properties well, and histology showed that severe IUGR had the lowest collagen to elastin ratio. 30409992 2018
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.150 Biomarker phenotype BEFREE We report intrauterine growth restriction (IUGR) increases vascular stiffening in both male and female rats through increased collagen content and altered elastin structure more than a high-fat diet (HFD) alone. 27881387 2017
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.150 Biomarker phenotype BEFREE Within the lung, FGR caused reduced secondary septal crest density and altered elastin deposition compared with controls. 28819007 2017
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.150 Biomarker phenotype HPO