ELN, elastin, 2006

N. diseases: 545; N. variants: 61
Disease: Liver Cirrhosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.220 Biomarker disease BEFREE Our findings strongly suggested that elastin crosslinking and LOXL1 were co-associated with liver cirrhosis, while selective inhibition of LOXL1 arrested disease progression by reducing crosslinking of elastin. 29366776 2018
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.220 Biomarker disease BEFREE Hepatic stellate cells (HSCs) are responsible for hepatic fibrosis and liver cirrhosis via their ability to produce extracellular matrices such as collagens and elastin. 28456722 2017
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.220 ModifyingMutation disease RGD Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis. 22223197 2012