ELN, elastin, 2006

N. diseases: 545; N. variants: 61
Disease: Dissection of aorta ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0340643
Disease: Dissection of aorta
Dissection of aorta 		0.040 AlteredExpression disease BEFREE In a mouse model for human AD, infusion of adeno-associated viruses (serotype 6) carrying antisense for miR-144-3p (as-miR-144-3p) under CAG promoter significantly reduced the incidence and severity of AD, seemingly through enhancement of TE levels in ASMC. 29487278 2018
CUI: C0340643
Disease: Dissection of aorta
Dissection of aorta 		0.040 Biomarker disease BEFREE The synthetic smooth muscle cells increase collagen synthesis and matrix metalloproteinase-2 production, both of which can promote collagen deposition and elastin degradation in thoracic aortic dissection. 22960022 2012
CUI: C0340643
Disease: Dissection of aorta
Dissection of aorta 		0.040 AlteredExpression disease BEFREE The serum levels of soluble elastin increase in patients with aortic dissection, but its distribution and characteristics are unclear. 19755752 2009
CUI: C0340643
Disease: Dissection of aorta
Dissection of aorta 		0.040 Biomarker disease BEFREE Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection. 16153447 2005