EN2, engrailed homeobox 2, 2020

N. diseases: 41; N. variants: 8
Disease: Social Communication Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0150080
Disease: Social Communication Disorder
Social Communication Disorder 		0.010 Biomarker disease BEFREE Engrailed-2 (En2) is a transcription factor critical for neural development, and mice lacking En2 (En2<sup>-/-</sup>) display signs of impaired social interaction, cognitive processes (e.g., learning and memory, conditioned fear), and neurodevelopmental alterations. 29953887 2018