ENG, endoglin, 2022

N. diseases: 371; N. variants: 114
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.260 Biomarker phenotype RGD We investigated the effect of magnesium sulfate (MgSO4) therapy on vascular endothelial growth factor (VEGF), placental growth factor (PlGF), nitric oxide (NO) metabolites, soluble fm-like tyrosine kinase-1 (sFlt-1) and endoglin levels in PE rats and the effect of this treatment on the feto-maternal outcome. 22763474 2012
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.260 Therapeutic phenotype RGD The effect of Kraussianone-2 (Kr2), a natural pyrano-isoflavone from Eriosema kraussianum, in an L-NAME- induced pre-eclamptic rat model. 22308016 2012
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.260 AlteredExpression phenotype LHGDN Soluble endoglin levels during normotensive and hypertensive pregnancies. 17964708 2008
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.260 AlteredExpression phenotype LHGDN However, an increased expression of ENG and FLT1 was detected by qRT-PCR in the PE + SGA group. 18330824 2008
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.260 Biomarker phenotype LHGDN First-trimester serum levels of soluble endoglin and soluble fms-like tyrosine kinase-1 as first-trimester markers for late-onset preeclampsia. 18771978 2008
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.260 Biomarker phenotype LHGDN A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate. 18175241 2008
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.260 Biomarker phenotype LHGDN Soluble endoglin (sEng) joins the soluble fms-like tyrosine kinase (sFlt) receptor as a pre-eclampsia molecule. 16870672 2006
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.260 Biomarker phenotype LHGDN Our results suggest that sEng may act in concert with sFlt1 to induce severe preeclampsia. 16751767 2006