EPAS1, endothelial PAS domain protein 1, 2034

N. diseases: 293; N. variants: 35
Disease: Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.060 AlteredExpression group BEFREE The high HIF-2α expression was associated with histology (squamous cell carcinoma vs. adenocarcinomas) in these patients ( p = 0.001). 28653893 2017
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.060 Biomarker group BEFREE Poorer outcome in stromal HIF-2 alpha- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis. 18728663 2008
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.060 AlteredExpression group LHGDN Increasing expression of hypoxia-inducible proteins in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence. 17437013 2007
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.060 AlteredExpression group LHGDN Stromal expression of hypoxia regulated proteins is an adverse prognostic factor in colorectal carcinomas. 17452775 2007
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.060 Biomarker group BEFREE The PAI-1 gene as a direct target of endothelial PAS domain protein-1 in adenocarcinoma A549 cells. 15039136 2004
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.060 AlteredExpression group LHGDN Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma. 12209691 2002