EPAS1, endothelial PAS domain protein 1, 2034

N. diseases: 293; N. variants: 35
Disease: Osteosarcoma of bone ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.050 AlteredExpression disease BEFREE Ezrin was downregulated in OS in hTEBOs with rhBMP-7, whereas HIF2α was significantly upregulated in comparison to hTEBOs without rhBMP-7. 30836200 2019
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.050 AlteredExpression disease BEFREE LncRNA HIF2PUT and HIF-2α were downregulated in osteosarcoma cell lines. 30966832 2019
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.050 Biomarker disease BEFREE In conclusion, knockdown of HIF-2α in the osteosarcoma cell line reduced the proliferation of cancer cells and increased apoptosis. 28259908 2017
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.050 AlteredExpression disease BEFREE Interestingly, the expression levels of HIF-2α mRNA in osteosarcoma tissues were positively correlated with those of HIF2PUT (r=0.28, P=0.009). 27623205 2016
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.050 AlteredExpression disease BEFREE HIF2PUT expression levels were positively correlated with HIF‑2α in osteosarcoma tissues. 25434862 2015