EPHA3, EPH receptor A3, 2042

N. diseases: 193; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.340 AlteredExpression disease BEFREE A comparison of EphA3 immunohistochemical scores for tumor and matched normal intestinal tissues revealed that the protein was downregulated in 82/164 (50.0%), unchanged in 52/164 (31.7%), and upregulated in 30/164 (18.3%) cases of CRC. 30560328 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.340 Biomarker disease BEFREE The most obvious finding to emerge from the analysis that novel synthesized sulfonamide derivative H-4i is effective on HT-29 more than HEK-293. 29520697 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.340 Biomarker disease BEFREE However, the role of EPHA3 in colorectal cancer has not been thoroughly investigated. 28169277 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.340 Biomarker disease BEFREE Our findings reveal the mechanisms underlying the oncogenic activities of EphA3 in colorectal cells, which could provide novel targets for the prevention, early diagnosis, and treatment of colorectal cancer. 27721017 2016
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.340 GeneticVariation disease UNIPROT