EPHA4, EPH receptor A4, 2043

N. diseases: 118; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.020 Biomarker disease BEFREE MiR-145 exerted a protective effects in cell viability in the OGD model by downregulating EPHA4, which suggested their potential roles in ischemic stroke and requires further research. 31150684 2019
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.020 AlteredExpression disease BEFREE In conclusion, the present study provides evidence that the activation of EphA4 induced by EphrinA1 contributes to BBB damage following ischemic stroke through the Rho/ROCK signaling pathway, which highlights a potential therapeutic strategy for ischemic stroke and may help the development of preventative interventions for VD. 30186497 2018