EPHA4, EPH receptor A4, 2043

N. diseases: 118; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.040 AlteredExpression phenotype BEFREE Moreover, our results demonstrated that miR-335 overexpression suppresses migration and invasion in MCF-7 and MDA-MB-231 cells, an effect that was reversed by EphA4 overexpression. 28795314 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.040 AlteredExpression phenotype BEFREE <b>Results:</b> EphA4 expression was significantly associated with vascular invasion (<i>P</i>=0.015), post-treatment depth of tumor invasion (<i>P</i>=0.006), pre-treatment and post-treatment lymph node metastasis (<i>P</i>=0.004 and <i>P</i>=0.011, respectively). 28529623 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.040 AlteredExpression phenotype BEFREE EphA4 gene expression is associated with an improved outcome in patients with resected lung adenocarcinoma, possibly by affecting cancer cell migration and invasion. 22807579 2012
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.040 AlteredExpression phenotype BEFREE EphA4 overexpression, at the protein level, was significantly associated with depth of invasion and recurrence. 18837080 2008