EPHB2, EPH receptor B2, 2048

N. diseases: 649; N. variants: 19
Disease: Adult Meningioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278877
Disease: Adult Meningioma
Adult Meningioma 		0.020 Biomarker disease BEFREE In addition, total and phosphorylated AKT, ERK, and FAK, which have been shown to be important drivers for meningioma cell proliferation, were markedly lower in silvestrol-treated Ben-Men-1 cells. 28610844 2018
CUI: C0278877
Disease: Adult Meningioma
Adult Meningioma 		0.020 Biomarker disease BEFREE Our findings provide strong evidence that RAS protein is highly expressed in meningioma cells, and the RAS activity is inhibited by downregulating ERK and AKT signal pathway, which may further inhibit the growth of meningioma. 27021020 2017