EPHX2, epoxide hydrolase 2, 2053

N. diseases: 97; N. variants: 20
Disease: Anorexia Nervosa ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.030 Biomarker disease BEFREE Collectively, our data suggest that dietary factors may contribute to the burden of EPHX2-associated AN susceptibility and affect disease outcome. 28232135 2017
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.030 Biomarker disease BEFREE Because epoxide hydrolase 2 (EPHX2) was identified as a novel AN susceptibility gene, and because its protein product, soluble epoxide hydrolase (sEH), converts bioactive epoxides of polyunsaturated fatty acid (PUFA) to the corresponding diols, lipidomic and metabolomic targets of EPHX2 were assessed to evaluate the biological functions of EPHX2 and their role in AN. 25824304 2016
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.030 GeneticVariation disease BEFREE These findings suggest a novel association of gene variants within EPHX2 to susceptibility to AN and provide a foundation for future study of this important yet poorly understood condition. 23999524 2014