EPHX2, epoxide hydrolase 2, 2053

N. diseases: 97; N. variants: 20
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.040 GeneticVariation disease BEFREE Human data show an association of sEH (Ephx2) gene polymorphisms with increased risk of atherosclerosis and cardiovascular diseases. 20425256 2010
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.040 GeneticVariation disease BEFREE This detailed investigation of the association of EPHX2 genetic variation with CAC supports EPHX2's emerging role as a risk factor for atherosclerosis, whose effects are influenced by smoking. 16545818 2007
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.040 GeneticVariation disease LHGDN This detailed investigation of the association of EPHX2 genetic variation with CAC supports EPHX2's emerging role as a risk factor for atherosclerosis, whose effects are influenced by smoking. 16545818 2007
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.040 GeneticVariation disease BEFREE Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. 16595607 2006
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.040 GeneticVariation disease BEFREE Twelve single nucleotide polymorphisms (SNPs) spanning EPHX2 were genotyped in a case-cohort sample of 1336 participants from the Atherosclerosis Risk in Communities (ARIC) study. 16115816 2005