ERBB2, erb-b2 receptor tyrosine kinase 2, 2064

N. diseases: 995; N. variants: 85
Disease: Benign Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.050 Biomarker group BEFREE The mRNA expression was reduced in patients with IDCA versus DCIS or benign tumors (benign vs IDCA, P < 0.0009; DCIS vs IDCA, P < 0.005), as well in HER-2/neu-positive tumors versus samples negative for receptors (P < 0.0024). 21750466 2011
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.050 Biomarker group BEFREE No amplification of EGFR and erbB2 genes was established in tumors with low malignant potency and in benign tumors. 16445625 2006
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.050 Biomarker group BEFREE The detection of low/intermediate/high risk genital groups of human papillomavirus (HPV) in correlation with a growth-factor receptor c-erbB-2 in benign tumors of the mammary nipple. 11299846 2001
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.050 Biomarker group BEFREE Only 1 of the 18 benign tumors had c-erbB-2/neu oncogene overexpression. 7870438 1995
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.050 Biomarker group BEFREE By contrast to a number of previous studies, none of the 19 malignant and 12 benign tumours showed ERBB2 (17q12-22) amplification. 7509629 1993