Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
0.040 PosttranslationalModification disease BEFREE The frequency of MGMT and ERCC1 methylation was significantly higher in rectum cancers than in benign tumors both for the tissue and the blood (p<0.001). 29080834 2018
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
0.040 AlteredExpression disease BEFREE ERCC1 overexpression is associated with a poor preoperative CRT response in patients with rectal cancer receiving FOLFOX-based preoperative CRT. 28608017 2017
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
0.040 Biomarker disease BEFREE This is the first work to propose variants within the AREG and the ERCC1 genes as promising predictive biomarkers of ypCR in rectal cancer. 25026457 2015
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
0.040 Biomarker disease BEFREE The results showed that XRCC1 RS25487, XRCC1 RS179978, XRCC3 RS861539, ERCC1 RS11615 and ERCC2 RS13181 were not associated with the response in the radiotherapy-based multimodality treatment of patients with rectal cancer (p>0.05). 25684513 2015