Disease: Leukopenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023530
Disease: Leukopenia
Leukopenia 		0.050 GeneticVariation disease BEFREE Patients with the A/A genotype in rs11615 of the ERCC1 gene had significantly higher risk of neutropenia (P = .0133). 31797573 2020
CUI: C0023530
Disease: Leukopenia
Leukopenia 		0.050 GeneticVariation disease BEFREE Multivariate analysis showed an association between specific <i>ERCC1/2</i> genotypes and cumulative dose of BEP drugs with the appearance of severe leukopenia and/or febrile neutropenia. 30914949 2019
CUI: C0023530
Disease: Leukopenia
Leukopenia 		0.050 GeneticVariation disease BEFREE ERCC1 and CYP2B6 gene polymorphisms were associated with the extent of grade 4 neutropenia in patients receiving AC chemotherapy. 27858847 2016
CUI: C0023530
Disease: Leukopenia
Leukopenia 		0.050 GeneticVariation disease BEFREE Neutropenia was more frequent in MTHFR 677TT [adjusted odds ratio (OR) 2.32, 95 % confidence interval (CI) 1.19-4.55] and ERCC1 19007TT (adjusted OR 4.58, 95 % CI 1.20-17.40) genotypes. 23314736 2013
CUI: C0023530
Disease: Leukopenia
Leukopenia 		0.050 GeneticVariation disease BEFREE In oxaliplatin-treated patients, carriers of one or two T variants of Asn118Asn ERCC1 SNP had a lower risk for neutropenia(OR = 0.205; 95 % CI = 0.061–0.690; P = 0.01) [corrected]. 23543295 2013