ERCC5, ERCC excision repair 5, endonuclease, 2073

N. diseases: 238; N. variants: 38
Disease: Malignant neoplasm of stomach ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE Subgroup analysis of geographic locations showed a significant association between the XPG gene rs2094258 polymorphism and GC risk in Southern China. 29732643 2018
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE To our knowledge, this is the first meta-analysis to investigate the association between rs751402 mutation located on the XPG promoter region and GC risk. 29148016 2018
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE The XPG gene rs751402 polymorphism is associated with an increased risk of GC in Chinese Han populations. 28832189 2017
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE The current meta-analysis demonstrated that the XPG gene polymorphism rs751402 was associated with increased susceptibility to gastric cancer in Chinese populations. 29049208 2017
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE In conclusion, we suggest that the ERCC5 rs751402 polymorphism is associated with development of gastric cancer. 27323183 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE Using unconditional logistic regression analysis, we found that neither of these ERCC5 variants was associated with increased risk of gastric cancer under co-dominant, dominant, or recessive models (P < 0.05). 27323158 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE Association between ERCC5 gene polymorphisms and gastric cancer risk in a Chinese population. 27051028 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE Association between XPG gene polymorphisms and development of gastric cancer risk in a Chinese population. 27323165 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE Previous studies have indicated some polymorphisms in the XPG gene are associated with stomach cancer susceptibility. 26820236 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE In conclusion, we suggest that the ERCC5 rs751402 gene polymorphism may influence the susceptibility to gastric cancer in the Chinese population. 27706622 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE ERCC5 rs751402 and rs2296147 polymorphisms might alter the risk of developing GC and especially the diffuse subtype. 22982416 2012
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations. 22371296 2012
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 Biomarker disease BEFREE In this study, we examined the polymorphisms of six DNA repair genes: APE1, HOGG1, XRCC1, XRCC3, XPD, and XPG in patients with gastric cancer (GC). 20530453 2010
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation disease BEFREE In conclusion, PTGS2 and ERCC5 were associated with stomach cancer risk in a Chinese population. 19661089 2009