ERG, ETS transcription factor ERG, 2078

N. diseases: 298; N. variants: 31
Disease: Seizures ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036572
Disease: Seizures
Seizures 		0.020 Biomarker phenotype BEFREE We found that the activity of the voltage-gated potassium channel seizure (sei), an ortholog of the mammalian ERG channel family, is essential for protecting flies from acute heat-induced seizures. 31393878 2019
CUI: C0036572
Disease: Seizures
Seizures 		0.020 GeneticVariation phenotype BEFREE Knockdown of ERG3 channels in hippocampus enhanced seizure susceptibility, while mice treated with the ERG channel activator NS-1643 were less prone to epileptogenesis. 30016551 2018