ESRRB, estrogen related receptor beta, 2103

N. diseases: 102; N. variants: 7
Disease: Brain Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.030 Biomarker group BEFREE Orphan nuclear receptor TLX (NR2E1) plays a critical role in the regulation of neural stem cells (NSC) as well as in the development of NSC-derived brain tumors. 30441799 2018
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.030 Biomarker group BEFREE The druggable orphan nuclear receptor TLX (NR2E1) is characterized as an important regulator of neural stem cells and is also implicated in the development of some brain tumours. 25557355 2015
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.030 Biomarker group BEFREE The orphan nuclear receptor TLX is required for proliferation of adult NSCs, and its upregulation promotes brain tumor formation. 23028043 2012