ETV4, ETS variant transcription factor 4, 2118

N. diseases: 120; N. variants: 14
Disease: Sarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.040 Biomarker group BEFREE The utility of ETV1, ETV4 and ETV5 RNA in-situ hybridization in the diagnosis of CIC-DUX sarcomas. 27790742 2017
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.040 AlteredExpression group BEFREE In summary, diffuse moderate-to-strong ETV4 expression is present in most CIC-rearranged sarcomas and unclassified round cell sarcomas. 27443513 2016
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.040 AlteredExpression group BEFREE We performed a detailed immunohistochemical analysis to investigate ETV4 expression in CIC-rearranged undifferentiated round-cell sarcomas and their potential mimics (especially Ewing sarcomas). 27562494 2016
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.040 GeneticVariation group BEFREE In the present study, we determined the genomic breakpoint and characterized the chimeric transcript of the EWSR1-ETV4 fusion gene in two t(17;22) Ewing sarcomas. 9858836 1998