ETV6, ETS variant transcription factor 6, 2120

N. diseases: 241; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 Biomarker disease BEFREE Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer. 29455655 2018
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 AlteredExpression disease BEFREE We present a molecular mechanism in which EGFR activation leads to the induction of miR-96 expression and suppression of ETV6, which contributes to prostate cancer progression. 27746161 2017
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 Biomarker disease BEFREE Although mutational analysis of ETV6 has not been examined previously in prostate carcinoma, it is an attractive candidate prostate cancer tumor suppressor gene since as it previously has been implicated in malignancy. 12210491 2002