|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
There were significant inverse correlations between serum albumin and Lp(a) (r = -0.33, p < 0.01), total cholesterol (r = -0.31, p < 0.01), LDL (r = -0.39, p < 0.01) or ApoB (r = -0.35, p < 0.01) in ESRD patients.
|
9237283 |
1997 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
There is no evidence that shifts of albumin to the extravascular space or that dilution of the plasma by volume expansion plays any role in causing hypoalbuminemia in ESRD patients.
|
9848794 |
1998 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
CTD_human |
[Experimental study on treatment of chronic renal failure with yishen qudu capsule].
|
11938814 |
2000 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
In a two-by-two factorial study of urinary albumin in non-diabetic Polynesians, 90 people with a first degree relative (FDR) with end-stage renal failure (ESRF) and diabetes (group 1) were compared with 90 people with a FDR with non-diabetic ESRF (group 2), with 90 people with a FDR with diabetes but no known nephropathy (group 3) and 90 people with no known relatives with either diabetes or nephropathy (group 4).
|
11168340 |
2001 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Genomic DNA was obtained from 659 patients: 307 with normal urinary albumin excretion despite diabetes duration of >15 years (control subjects) and 352 with advanced diabetic nephropathy, of whom 200 had persistent proteinuria and 152 had end-stage renal disease (ESRD).
|
11916943 |
2002 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
When comparing patients with a mutant allele with the wild genotype there was no difference between the patients with end-stage renal disease, proteinuria, microalbuminuria, and those with a normal albumin excretion rate (df =3, chi2 =1.62, 1.31 and 0.77).
|
12631336 |
2003 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Elevated urinary albumin excretion and decreased glomerular filtration rate (GFR) are risk factors for cardiovascular death and end-stage renal disease in individuals with type 2 diabetes mellitus (DM).
|
15112169 |
2004 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
An increase in the ratio of oxidized to unoxidized albumin was determined using 5/6 nephrectomized rats (CRF rats) compared to a control group.
|
17387602 |
2007 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Diabetic nephropathy was defined as macroalbuminuria (urinary albumin excretion rate >200 microg/min or >300 mg/24 h) or end-stage renal disease.
|
17337502 |
2007 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Participants from the Epidemiology of Diabetes Complications Study with DNA available were studied for the incidence of microalbuminuria (albumin excretion rate [AER] 20-200 microg/min), macroalbuminuria (AER >200 microg/min), ESRD (renal dialysis or transplantation), and renal function decline (a decline > or =30 ml/min per 1.73 m(2) from baseline estimated [by the Cockcroft-Gault equation] glomerular filtration rate [eGFR] in those with baseline eGFR >60 ml/min per 1.73 m(2)).
|
19720796 |
2009 |
|
Kidney Failure, Chronic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
A significant negative correlation was observed between albumin levels and fat mass in both healthy subjects and inflamed ESRD patients.
|
22675238 |
2012 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Surprisingly, patients that reached end stage renal failure (ESRF) had a less severe nephrosis compared to those that did not develop ESRF; serum albumin 33 g/L (3.3 g/dL) versus 24 g/L (2.4 g/dL), p = 0.002 and urinary protein creatinine ratio (uPCR) 550 mg/mmol (5500 mg/g) versus 902 mg/mmol (9020 mg/g), p = 0.0124.
|
28637442 |
2017 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
In patients with end-stage renal disease (ESRD), phenytoin-albumin binding is altered and, thus, affects interpretation of total serum levels.
|
28470115 |
2017 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Thus, lower eGFR and higher urinary albumin values are not only predictors of progressive kidney failure, but also of all-cause and CV mortality, independent of each other and of traditional CV risk factors.Although subjects with ESRD are at the highest risk of CV diseases, there will likely be more events in subjects with mil-to-moderate renal dysfunction, because of its much higher prevalence.These findings are even more noteworthy when one considers that a mild reduction in renal function is very common in hypertensive patients.The current European Society of Hypertension (ESH)/European Society of Cardiology (ESC) guidelines for the management of arterial hypertension recommend to sought in every patient signs of subclinical (or asymptomatic) renal damage.
|
27873229 |
2017 |
|
Kidney Failure, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In the Atherosclerosis Risk in Communities Study (n = 13,277 from 4 US communities), we used structural equation modeling to estimate the association between serum 1,5-AG levels and end-stage renal disease (ESRD) from baseline (1990-1992) through 2013 with adjustment for demographics, risk factors, a latent variable for glycemia (diabetes status, fasting glucose, glycated hemoglobin (HbA1c), fructosamine, glycated albumin), and a latent variable for kidney function (creatinine, cystatin C, β2-microglobulin).
|
28535187 |
2017 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Of 256 participants (mean ± SD glomerular filtration rate [iothalamate] = 148 ± 45 mL/min, and median [interquartile range] urine albumin/creatinine = 39 [14-221] mg/g), 76 developed ESRD and 125 died during a median follow-up period of 15.2 and 15.7 years, respectively.
|
28934744 |
2017 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Normal or mildly increased 24-hour urinary albumin excretion (<30mg/d) at baseline was present in 28% of participants, but in only 5% of those progressing to ESKD.
|
29784612 |
2018 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
p-Cresyl glucuronide (p-CG) is a by-product of tyrosine metabolism that accumulates in patients with end-stage renal disease. p-CG binding to human serum albumin in physiological conditions (37 °C, pH 7.40) was studied by ultrafiltration (MWCO 10 kDa) and data were analyzed assuming one binding site.
|
29705133 |
2018 |
|
Kidney Failure, Chronic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The primary predictive factors were the 4-variable (age, sex, bedside Schwartz estimated glomerular filtration rate, and ratio of albumin to creatinine levels) and 8-variable (4 variables plus serum calcium, phosphate, bicarbonate, and albumin levels) KFREs, which provide 1-, 2-, and 5-year estimates of the risk of progression to ESRD.
|
29255845 |
2018 |
|
Kidney Failure, Chronic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Thirty-one children with ESRD and 18 healthy age- and sex-adjusted controls underwent measurement of serum levels of MMP-2, MMP-9, soluble E-selectin, phosphorus, calcium, parathyroid hormone, lipid profile, thrombotic factors, and albumin.
|
29891747 |
2018 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
In multivariate analysis, the likelihood of CVC use was lower with increasing dialysis vintage, OR 0.40 (0.26-0.60) for 4 years vs 1 year vintage, rising serum albumin, OR 0.73 (0.59-0.90) per 5 g/L), and with cystic disease as a cause of ESKD, OR 0.38 (95% CI 0.21-0.6).
|
29609535 |
2018 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Baseline serum albumin concentration was the predictor variable, and hazard ratios (HRs) for incident ESRD (from US Renal Data System linkage) were calculated in sequentially adjusted models.
|
29281114 |
2018 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
When analyzing S-Alb to predict mortality risk in ESRD, it should always be combined with measurement of hsCRP.
|
29926516 |
2018 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Low serum albumin level is an independent risk factor for ESRD in patients with IgAN.
|
29795559 |
2018 |
|
Kidney Failure, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Micro- and macroalbuminuria were defined as an albumin excretion rate of 20-199 and ≥200 μg/min, respectively, and end-stage renal disease (ESRD) was defined as dialysis or kidney transplantation.
|
28931542 |
2018 |