F2, coagulation factor II, thrombin, 2147

N. diseases: 61; N. variants: 24
Disease: Myocardial Infarction ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 Biomarker disease CTD_human Our findings suggest that the 20210 G-->A mutation in the prothrombin gene is a genetic risk factor for MI. 10027711 1999
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 Biomarker disease CTD_human When a coagulation defect was present (ie, the 20210 AG prothrombin genotype or the factor V Leiden mutation), the risk of myocardial infarction for carriers versus noncarriers was 1.4 (95% CI, 0.9 to 2.2). 9531249 1998
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 Biomarker disease CTD_human A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women. 9292507 1997