F2, coagulation factor II, thrombin, 2147

N. diseases: 490; N. variants: 42
Disease: Hereditary hyperhomocysteinemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2585350
Disease: Hereditary hyperhomocysteinemia
Hereditary hyperhomocysteinemia 		0.010 GeneticVariation disease BEFREE Mutations like factor V Leiden, prothrombin gene variant 20210A, and hereditary hyperhomocysteinemia are associated with an increased risk for thromboembolism as compared to mutations in natural inhibitors of coagulation. 16432849 2006