F2R, coagulation factor II thrombin receptor, 2149

N. diseases: 347; N. variants: 10
Disease: Chronic Obstructive Airway Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.030 GeneticVariation disease BEFREE In conclusion, we found that the PAR1 IVS-14 A/T rs168753 polymorphism was associated with the development of COPD. 26535635 2015
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.030 GeneticVariation disease BEFREE The aim of this study was to investigate the role of the promoter single-nucleotide polymorphism (SNP) rs2227744G>A in modulating PAR-1/F2R gene expression in the context of chronic obstructive pulmonary disease (COPD) and COPD exacerbations. 24973402 2014
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.030 AlteredExpression disease BEFREE PAR-1 protein overexpression in AMs from smokers might be important in the pathophysiology of chronic airways disease. 12589358 2003