F5, coagulation factor V, 2153

N. diseases: 369; N. variants: 52
Disease: Familial (FPAH) ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		0.050 Biomarker disease BEFREE The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). 23054468 2013
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		0.050 GeneticVariation disease BEFREE Factor V Leiden and the common haemochromatosis mutation HFE C282Y: is there an association in familial venous thromboembolic disease? 10520044 1999
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		0.050 GeneticVariation disease BEFREE Because patients with rare familial homocystinuria who also carry factor V Leiden have an increased incidence of venous thromboembolism (VTE), we hypothesized an interrelation of moderate hyperhomocyst(e)inemia, factor V Leiden, and risk of VTE in the general population. 9107163 1997
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		0.050 GeneticVariation disease BEFREE Factor V Leiden, an R506Q mutation in the gene coding for factor V, is the most common cause of familial thrombosis and could be a potentiating factor. 8592550 1996
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		0.050 GeneticVariation disease BEFREE Biochemical prototype for familial thrombosis. A study combining a functional protein C mutation and factor V Leiden. 7489240 1995