F10, coagulation factor X, 2159

N. diseases: 228; N. variants: 44
Disease: Factor V Leiden mutation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0584960
Disease: Factor V Leiden mutation
Factor V Leiden mutation 		0.030 Biomarker disease BEFREE No significant interference of RIV on APCr results obtained by a prothrombinase-based assay was observed for drug concentrations up to 400 ng/mL in FV wild-type and FVL carriers (homozygous and heterozygous). 28318106 2017
CUI: C0584960
Disease: Factor V Leiden mutation
Factor V Leiden mutation 		0.030 Biomarker disease BEFREE The cohort was found to have a mean FVL of 49.5±5.6% and this was positively correlated to the total number of circulating CD41a+MP (R=0.31, p=0.03) but not to other MP subsets or to MP prothrombinase activity. 21798575 2012
CUI: C0584960
Disease: Factor V Leiden mutation
Factor V Leiden mutation 		0.030 Biomarker disease BEFREE In conclusion, APTT-based assays, but not direct factor X activation-based assays, effectively detect the risk for venous thrombosis independent of FVL. 16601846 2006