FAAH, fatty acid amide hydrolase, 2166

N. diseases: 177; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain
0.010 GeneticVariation disease BEFREE To further understand the human implications of the interaction between these two systems, we investigated the role of the common, functional missense variant Pro129Thr of the gene coding fatty acid amide hydrolase (FAAH), the major degrading enzyme of endocannabinoids, on psychophysical and neurotransmitter (dopaminergic, opioid) responses to pain and placebo-induced analgesia in humans. 24042479 2014