FABP4, fatty acid binding protein 4, 2167

N. diseases: 194; N. variants: 5
Disease: Acute monocytic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.020 Biomarker disease BEFREE Fatty acid-binding protein FABP4 mechanistically links obesity with aggressive AML by enhancing aberrant DNA methylation in AML cells. 27885273 2017
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.020 Biomarker disease BEFREE In acute monocytic leukemia (AMoL) cells, the prevention of spontaneous apoptosis by bone marrow adipocytes was associated with an increase in fatty acid β-oxidation (FAO) along with the upregulation of <i>PPARγ, FABP4, CD36</i>, and <i>BCL2</i> genes. 28108519 2017