FABP2, fatty acid binding protein 2, 2169

N. diseases: 65; N. variants: 2
Disease: Hyperinsulinism ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020459
Disease: Hyperinsulinism
Hyperinsulinism 		0.030 Biomarker disease BEFREE A transition G to A at codon 54 of FABP2 was associated with high insulin resistance and different dietary response. 18701184 2008
CUI: C0020459
Disease: Hyperinsulinism
Hyperinsulinism 		0.030 GeneticVariation disease BEFREE These results suggest that the Ala54Thr substitution in the FABP2 gene is associated with increased fat oxidation and hyperinsulinemia in normal Korean men, but these effects are not mediated by an increase in the intestinal fatty acid absorption. 11288045 2001
CUI: C0020459
Disease: Hyperinsulinism
Hyperinsulinism 		0.030 GeneticVariation disease BEFREE These results suggest that in African-Americans, these variants in the IRS-1 and FABP2 genes are not associated with the risk of type 2 diabetes, severe obesity, or marked hyperinsulinemia, but that their independent and joint effects may be associated with small increases in BMI. 10480621 1999