|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In particular, FTO and FABP2 gene polymorphisms were significantly associated with susceptibility to MS and obesity in this cohort.
|
28738793 |
2017 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The FABP2 Ala54Thr polymorphism was significantly associated with obesity (AT vs AA: OR = 2.633, 95%CI = 1.065-6.663, P = 0.036; TT vs AA: OR = 4.160, 95%CI = 1.609-10.757, P = 0.003) and metabolic syndrome (TT vs AA: OR = 2.273, 95%CI = 1.242-4.156, P = 0.008) by logistic regression with adjustment for covariates.
|
25730055 |
2015 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The fatty acid binding protein 2 (FABP2) polymorphism Ala54Thr and obesity in Pakistan: A population based study and a systematic meta-analysis.
|
26238699 |
2015 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of our study was to investigate the influence of the Thr54 polymorphism in the FABP2 gene on obesity anthropometric parameters and cardiovascular risk factors in the fasted state in obese subjects and the allelic distribution of this polymorphism in a geographic area of Spain.
|
21079390 |
2010 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
The FABP2 gene has been proposed as a candidate gene for diabetes and obesity.
|
20202768 |
2010 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of our study was to investigate the influence of Thr54 polymorphism in the FABP2 gene on obesity anthropometric parameters, cardiovascular risk factors, and adipocytokines in patients with presurgical morbid obesity.
|
19475463 |
2009 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
FABP2 A54T polymorphism may help identify Caucasian subjects at risk for obesity.
|
19324445 |
2009 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of our study was to investigate the influence of Thr54 polymorphism in the FABP2 gene on obesity anthropometric parameters and cardiovascular risk factors.
|
17992640 |
2007 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Lack of association between the fatty acid binding protein 2 (FABP2) polymorphism with obesity and insulin resistance in two aboriginal populations from Chile.
|
17211557 |
2006 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort.
|
16718632 |
2006 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, Thr54 allele of FABP2 has associations with lower adjusted resting metabolic rate, resistance in reducing visceral white adipose tissue (WAT) and early onset of obesity in Japanese obese women.
|
15620432 |
2005 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Intestinal FABP2 A54T polymorphism: association with insulin resistance and obesity in women.
|
14981227 |
2004 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These results therefore suggested that the effects of the FABP2 polymorphism on TG, LDL-C and body mass index were associated with gender difference and obesity amongst non-diabetic Japanese-American subjects.
|
14686962 |
2004 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Genetic variation of fatty acid binding protein 2 (FABP2) may contribute to the high prevalence of obesity and Type II diabetes in Tonga.
|
12855223 |
2003 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A missense mutation (A54T) in the fatty acid binding protein type 2 (FABP2) gene has been associated with insulin resistance and obesity.
|
11707533 |
2001 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our data suggested that Ala54Thr polymorphism of the FABP2 gene is not a major contributing factor for obesity and obesity with dyslipidemia in Japanese children.
|
11866034 |
2001 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
(1) The Ala54 and Thr54 allele frequencies in Chinese were 0.71 and 0.29 respectively; (2) The FABP2-Ala54Thr variation was neither associated with fasting and post-challenged plasma glucose levels nor with NIDDM; (3) This variation was neither associated with fasting lipid profile nor with obesity; (4) The IGT subjects with genotype Thr54(+) (Thr54 homozygotes and heterozygotes) had lower fasting, 2-hour and total C-peptide levels and smaller AUC representing lesser C-peptide secretion after glucose challenge than those with genotype Thr54(-) (Ala54 homozygotes) (P = 0.04, 0.03, 0.01 and 0.01 respectively).
|
11593593 |
1999 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These results suggest that the polymorphism at codon 54 of the FABP2 gene is not a major contributing factor to obesity and insulin resistance in Japanese subjects.
|
10337870 |
1999 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We conclude that obesity is not associated with specific variants in the FABP2 gene.
|
9253345 |
1997 |