ALDH2, aldehyde dehydrogenase 2 family member, 217

N. diseases: 287; N. variants: 18
Disease: Alcoholic Intoxication ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.340 Biomarker disease BEFREE Main effects of ALDH2*2(-) and having more friends who got drunk were associated with greater alcohol consumption. 28471244 2017
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.340 GeneticVariation disease BEFREE Subjective feelings of alcohol intoxication in Asians with genetic variations of ALDH2 alleles. 1443441 1992
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.340 GeneticVariation disease BEFREE The results indicate that Japanese with the atypical ALDH2(2) allele are at a much lower risk in developing the alcoholic liver diseases than are those with homozygous, usual (Caucasian-type) ALDH1(2)/ALDH1(2), presumably owing to their sensitivity to alcohol intoxication. 3189338 1988
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.340 Biomarker disease BEFREE A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the ALDH2 isozyme, which has a low apparent Km for acetaldehyde. 7180842 1982