ALDH2, aldehyde dehydrogenase 2 family member, 217

N. diseases: 287; N. variants: 18
Disease: Hangover from alcohol ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0393756
Disease: Hangover from alcohol
Hangover from alcohol 		0.340 GeneticVariation phenotype BEFREE A standardized extract of the fruit of Hovenia dulcis alleviated alcohol-induced hangover in healthy subjects with heterozygous ALDH2: A randomized, controlled, crossover trial. 28750942 2017
CUI: C0393756
Disease: Hangover from alcohol
Hangover from alcohol 		0.340 GeneticVariation phenotype BEFREE Therefore, Korean pear juice may alleviate alcohol-hangover and its detoxification of alcohol seems to be modified by the genetic variation of ALDH2. 23587660 2013
CUI: C0393756
Disease: Hangover from alcohol
Hangover from alcohol 		0.340 GeneticVariation phenotype BEFREE Alcohol consumption is inhibited by the presence of inactive aldehyde dehydrogenase-2 (ALDH2) whose carriers are susceptible to alcohol flushing and hangovers. 22234728 2012
CUI: C0393756
Disease: Hangover from alcohol
Hangover from alcohol 		0.340 Biomarker phenotype BEFREE For men who usually consumed <44 g of ethanol/day, the median amount of drinking before hangover was significantly lower for ALDH2*1/2*2 men than for ALDH2*1/2*1 men reporting the same level of consumption. 16046871 2005